高分辨磁共振T2WI对面神经炎的诊断价值
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四川省医疗卫生与健康促进会项目(KY2022QN0355 )


Diagnostic value of high-resolution MRI T2WI for facial neuritis
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    摘要:

    目的 探讨3.0T高分辨磁共振T2加权成像(T2WI)对面神经炎的诊断价值。方法 选取2023年9—12月我院收治的50例临床诊断为面神经炎的患者,采用三维可变翻转角快速自旋回波T2WI进行扫描。基于原始影像数据,分别进行最大密度投影(MIP)重建及曲面重组(CPR)重建。系统评估面神经炎的成像特征、神经受累节段,并与瞬目反射检查结果进行对比分析。最终量化比较患侧与健侧面神经的直径差异及相对信号强度差异。结果 50例面神经炎患者,42例成功完成扫描,30例能在磁共振图像上观察到面神经炎,其中鼓室段16例(53%),乳突段23例(77%),腮腺段11例(37%),鼓室-乳突段均受累10例(33%),乳突-腮腺段均受累7例(23%),鼓室-乳突-腮腺段均受累3例(10%),两名放射科医师的对面神经炎诊断的一致性评价较好,Kappa值>0.75;轻度面神经炎的检出率为为64%,与瞬目反射的检查结果有统计学差异(P<0.05),重度面神经炎的检出率为86%,与瞬目反射的检查结果相比无统计学差异(P>0.05);患侧与健侧面神经直径比较差异有统计学意义(P<0.05),患侧与健侧面神经信号强度比值比较差异有统计学意义(P<0.05);面神经直径和信号强度比值的ROC曲线下面积分别为0.909(最佳截断值为1.62 mm,敏感性83.33%,特异性90.00%),0.876(最佳截断值为1.99,敏感性76.67%,特异性80.00%),面神经直径和信号强度比值联合诊断的ROC曲线下面积为0.959,敏感性为96.67%,特异性为83.33%。结论 基于高分辨磁共振T2加权成像的MIP及CPR图像能够清楚地显示面神经且能够有效用于重度面神经炎的诊断,面神经直径和信号强度比值可作为诊断面神经炎的重要指标

    Abstract:

    Objective To explore the diagnostic value of 3.0T magnetic resonance high-resolution T2-weighted imaging for facial neuritis. Methods This study enrolled 50 patients clinically diagnosed with facial neuritis who were admitted to our hospital from September to December 2023. All subjects underwent three-dimensional variable flip angle fast spin-echo T2-weighted imaging (T2WI) scans. Based on the original imaging data, both maximum intensity projection (MIP) reconstruction and curved planar reformation (CPR) reconstruction were performed. The imaging characteristics of facial neuritis and the involved nerve segments were systematically evaluated, with comparative analysis against blink reflex test results. Finally, quantitative comparisons were made between the affected and unaffected sides regarding facial nerve diameter differences and relative signal intensity differences. Results Among 50 patients with facial neuritis, 42 cases successfully completed scanning, 30 cases were able to observe facial neuritis on magnetic resonance imaging.16 cases (53%) were involved in the tympanic segment, 23 cases (77%) in the mastoid segment, 11 cases (37%) in the parotid segment. 10 cases (33%) were involved in both the tympanic and mastoid segments, 7 cases (23%) were involved in both the mastoid and parotid segments, 3 cases (10%) were involved in all three segments. The consistency evaluation of the diagnosis of facial neuritis by two radiologists was good, with Kappa values>0.75.The detection rate of mild facial neuritis was 64%, which was statistically different from the results of blink reflex examination (P<0.05). The detection rate of severe facial neuritis was 86%, which was not statistically different from the results of blink reflex examination (P>0.05).The diameter of the affected and healthy side nerves were (1.71±0.09 mm, 1.47±0.14 mm, P<0.05). The ratio of nerve signal intensity between the affected and healthy sides was (2.31 0.28, 1.88±0.23, P<0.05).The areas under the ROC curves for the diameter of facial nerve and the ratio of signal intensity were 0.909 (with an optimal cut-off value of 1.62mm, sensitivity of 83.33%, and specificity of 90.00%) and 0.876 (with an optimal cut-off value of 1.99, sensitivity of 76.67%, and specificity of 80.00%), respectively. The area under the ROC curve for the combined diagnosis of facial nerve diameter and signal intensity ratio was 0.959, with a sensitivity of 96.67% and a specificity of 83.33%. Conclusion MIP and CPR images based on high-resolution T2 weighted magnetic resonance imaging can clearly display the facial nerve and it can be effectively used for the diagnosis of severe facial neuritis. The diameter of facial nerve and the ratio of signal intensity can be used as important indicators for the diagnosis of facial neuritis

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  • 在线发布日期: 2026-04-17
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