Objective The relationship between left atrial appendage morphology and related parameters and cardiac dysfunction in non-valvular atrial fibrillation in Xinjiang was analyzed by dual-source CT. Methods A retrospective analysis of 650 patients with non-valvular atrial fibrillation (NVAF) who were hospitalized in the People 's Hospital of Xinjiang Uygur Autonomous Region from January 2022 to June 2024, including 330 cases in the case group (patients with cardiac insufficiency) and 320 cases in the control group (patients without heart failure), and underwent left atrial pulmonary vein dual-source CT imaging. The clinical data, left atrial appendage anatomical morphology and related parameters of the patients were collected, and the relationship between left atrial appendage anatomical morphology and related parameters and cardiac insufficiency was analyzed by binary unconditional logistic regression analysis. Results Compared with the general data of the two groups, the age, creatinine value, uric acid value, triglyceride (TG), incidence of persistent atrial fibrillation, prevalence of coronary heart disease and hypertension, left ventricular end-diastolic diameter (LVEDV) and left ventricular end-systolic diameter (LADV) of the case group were higher than those of the control group (P<0.05 ).The CHA2DS2-VASc score and LVEF in the case group were lower than those in the control group (P<0.05 ). Comparison of CTA parameters of left atrial appendage morphology showed that there was no significant difference in left atrial appendage morphology between the case group and the control group (P>0.05 ).Binary logistic regression analysis showed that age (OR=1.055, β=0.054,95%CI 1.009~1.104 ), LVEF(OR=0.505, β=〖CD*3/5〗0.683,95%CI 0.443~0.575 ), coronary heart disease (OR=4.803, β=1.569,95%CI 2.060~11.2 ), left atrial appendage volume (OR=1.217, β=0.196,95%CI 1.042~1.421 ) were independent risk factors for heart failure. Conclusion The enlargement of the left atrial volume in patients with atrial fibrillation may be a risk factor for heart failure. The shape of the left atrium (chicken wing type, cauliflower type, wind vane type, cactus type) is not a risk factor for heart failure in patients with atrial fibrillation