认知行为疗法治疗慢性主观性耳鸣的meta分析
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四川省医学科技创新研究会科研课题(YCH-KY-YC ZD2024-266)


Effects of cognitive behavioral chronic subjective therapy on tinnitus: a meta analysis
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    目的 通过meta分析探讨认知行为疗法对慢性主观性耳鸣的疗效。方法 全面检索中英文关于认知行为疗法治疗慢性主观性耳鸣相关的随机对照实验,纳入研究对象的耳鸣病程均需≥3个月,且排除器质性耳鸣,以单一认知行为疗法或联合其他治疗为观察组而对照组不可包含认知行为疗法的研究,提取耳鸣相关耳鸣致残量表(THI)、耳鸣功能指数(TAQ)、失眠严重程度指数(ISI)、医院焦虑抑郁量表(HADS)、耳鸣问卷(TQ)、抑郁量表(SDS)等各量表评分数据,采用Revman5.4软件进行meta分析。结果 共纳入16篇文献,19组数据进行meta分析,分别提取各个研究中各个量表评分的数据行meta分析后,分别针对有效率、耳鸣严重程度、睡眠情况、焦虑抑郁情况进行分析。认知行为疗法的总有效程度是对照组的2.37倍;针对评估耳鸣严重程度的量表THI、TQ、mini-TQ结果有不统一,显示认知行为治疗(CBT)可改善或无明显效果;针对评估失眠严重程度的ISI量表、匹兹堡睡眠治疗匹兹堡睡眠治疗指数(PSQI),CBT可使其状况改善;针对评估患者不良心理状况的HADS,以及评估焦虑情况的焦虑问卷(TAQ)、焦虑量表(SAS)量表和抑郁状况的SDS量表,结果显示CBT可能导致分化的结果。结论 认知行为疗法对于耳鸣有显著治疗效果且具有统计学意义,可改善耳鸣的症状以及患者的睡眠状况,针对焦虑和抑郁治疗效果则可能不确定

    Abstract:

    Objective To investigate the efficacy of cognitive-behavioral therapy (CBT) for chronic subjective tinnitus through a meta-analysis. Methods A comprehensive search was conducted for randomized controlled trials on CBT for chronic subjective tinnitus, including studies with tinnitus duration ≥3 months and excluding objective tinnitus. The intervention group received either CBT alone or in combination with other treatments, while the control group did not receive CBT. Outcome measures such as THI, TAQ, ISI, HADS, TQ and SDS were extracted for meta-analysis using Revman 5.4 software. Results A total of 16 articles with 19 data sets were included for meta-analysis. After analyzing the extracted data from each study for various outcome measures, the meta-analysis was performed on treatment efficacy, tinnitus severity, sleep quality, and anxiety and depression levels. The overall effective rate of cognitive behavioral therapy (CBT) was 2.37 times that of the control group. For the tinnitus severity assessment scales THI, TQ, and mini-TQ, the results were inconsistent, indicating that CBT might improve symptoms or had no significant effect. Regarding the evaluation of insomnia severity using the ISI scale and the Pittsburgh Sleep Quality Index (PSQI), CBT could lead to improvements in these conditions. When assessing patients' adverse psychological conditions through the HADS, as well as anxiety through the TAQ and SAS scales, and depression through the SDS scale, the results suggested that CBT might yield differentiated outcomes. Conclusion Cognitive behavioral therapy has a significant and statistically significant therapeutic effect on tinnitus, improving tinnitus symptoms and sleep quality in patients. However, the results for anxiety and depression measures are contradictory across different scales

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李雯彬,刘倩,杨晓妹,等.认知行为疗法治疗慢性主观性耳鸣的meta分析[J].西部医学,2025,37(10):1521-1528.

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  • 在线发布日期: 2025-10-20
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