Objective To analyze the correlation between the risk of esophagogastric varices bleeding（EVB）and glucose metabolism disorders in patients with hepatitis B virus related liver cirrhosis (LC-B).Methods A total of 146 patients with LC-B admitted to the Affiliated Hospital of Zunyi Medical University and Suining Central Hospital from September 2014 to August 2022, who completed gastroscopy and oral glucose tolerance test (OGTT) examinations, were selected as the study subjects. According to the extent of esophagogastric varices in the gastroscopy, high-risk varices (HRVs) were determined. “HRVs” were defined as medium/large varices or small varices with red wale marks. The correlation between HRVs and glucose metabolism disorders was analyzed. Results The study include 146 patients with LC-B according to the inclusion criteria. Among them, there were 50 patients (34.2%) with HRVs and 96 patients (65.8%) without HRVs. There were 50 patients with normal glucose tolerance (NGT) (34.2%), 53 patients with impaired glucose tolerance (IGT) (36.3%), and 43 patients with hepatogenous diabetes (HD) (29.5%). The levels of prothrombin activity, leukocytes, hemoglobin, platelets, alanine aminotransferase (ALT), cholinesterase, albumin, aspartate aminotransferase (AST), glutamyltransferase, and prealbumin in patients with HRVs were significantly lower than those in patients without HRVs (P＜0.05). The prothrombin time, AST/ALT, total bile acid, liver fibrosis factor 4 index, Child-Pugh score, end-stage liver disease score, liver stiffness measurement, and portal vein diameter in patients with HRVs were significantly higher than those in patients without HRVs (P＜0.05).22(51.2%) of 43 patients with HD were associated with HRVs, which was significantly higher than that in patients with NGT (24%) (P=0.009), but there was no statistical difference when compared with that inpatients with IGT (30.2%) (P＞0.05), and there was no significant difference in HRVs prevalence between the patients with IGT and NGT(P＞0.05). The incidence of HD in patients with HRVs was also significantly higher than that in patients without HRVs. Conclusion The occurrence of high-risk varices in patients with LC-B is related to the degree of liver injury and the degree of glucose metabolism disorders. The incidence of high-risk varices in patients with HD is significantly higher than that in patients with NGT, and the incidence rate of HD in patients with high-risk varices is also significantly higher than that in patients without high-risk varices