Objective To explore and analyze the outcome of pregnancy patients with heart disease under the multidisciplinary team (MDT) mode. Methods A total of 81 pregnant women with heart disease who were treated in MDT mode in The Second Affiliated Hospital of Army Medical University from April 2021 to April 2022 were selected as the research objects. According to the recommended outcomes, the patients were divided into those who could continue pregnancy and those who were recommended to terminate pregnancy. t test, one-way analysis of variance (ANOVA) and rank sum test were used to analyze the age, outcome and number of pregnant women. Chi-square test and Logistic regression were used to analyze the influence of maternal age, gestational age, type of heart disease, grade of cardiac function and grade of pulmonary hypertension on the recommended outcomes and actual outcome. The difference between the actual outcome of pregnancy complicated with heart disease and the recommended outcome was measured by crosstabs. SPSS 20.0 statistical software was used for all statistics, and P＜0.05 was considered statistically significant. Results There was no statistically significant difference in pregnancy outcomes between the types of maternal heart disease, but there were statistically significant differences in pregnancy outcomes between pulmonary hypertension grade and cardiac function grade. Logistic regression analysis showed that the effect of cardiac function grade on pregnancy outcome was statistically significant (OR=2.51,P＜0.05). The grade of pulmonary hypertension had a statistically significant effect on the pregnancy outcome (OR=2.02,P＜0.05). The actual outcome of pregnancy complicated with heart disease was statistically different from the recommended outcome, but the type of heart disease, the grade of heart function and the grade of pulmonary hypertension had no statistically significant effect on the actual outcome. Conclusion MDT recommends that most pregnant women with heart disease can continue pregnancy with MDT diagnosis or under strict monitoring. Pregnancy outcomes are not significantly affected by the type of heart disease, but the grade of cardiac function and pulmonary hypertension have a significant impact on pregnancy outcomes. However, the factors that influenced the suggested outcome has no significant effect on the actual outcome, but it is more about patients' wishes and providing the patients with strictly medical monitoring, and most patients will have good practical outcomes