Abstract:Objective To explore the correlation of anti-Müllerian hormone (AMH) level with thyroid autoantibodies and the thyroid function indicators in women of childbearing age, so as to provide guidance on prenatal and postnatal care. 〖WTHZ〗Methods 2, 833 women of childbearing age from 18 to 50 (mean 33.68 ± 7.05) years who visited a top level hospital in Xinjiang from 2015 to 2021 were collected as the study subjects. AMH levels in each group were compared by age and thyroid autoantibody levels, and the correlation between the thyroid function indicators and AMH level was analyzed. Results In the study population, the AMH level was 1.92 (0.62,3.74) μg /L, the positive rate of TgAb was 22.06%, the positive rate of TPOAb was 22.66%,the detection rate of Hashimoto's thyroiditis (HT) was 32.12%. With increasing age, AMH tended to decrease, while TSH and TPOAb and TgAb titers tended to increase, with statistically significant differences (P<0.05). Compared with the antibody-negative group, the groups positive for TPOAb alone and for both TgAb and TPOAb had older age, lower AMH levels, and higher FSH, FT3, and FT4 levels, with statistically significant differences (P<0.05). Compared with the group positive for TgAb alone, the group positive for TPOAb alone had older age and higher FSH, FT3, and FT4 levels, and the group positive for both TgAb and TPOAb had higher FSH and FT4 levels, with statistically significant differences (P<0.05) .After controlling for age, AMH showed a very weak positive correlation with FT4 (r1=0.039, P1=0.038), and a very weak negative correlation with TPOAb (r1=-0.038, P1=0.045). Conclusion Thyroid autoantibodies are related to the ovarian reserve function . It is recommended to educate the patient and perform thyroid function screening and AMH testing before preparing for pregnancy