Objective To explore the correlation between laryngopharyngeal reflux disease (LPRD) and Lingual Tonsillar Inflammatory Changes. Methods Patients who visited Otolaryngology Head and Neck Surgery Clinic of The First Affiliated Hospital of Bengbu Medical College from May 2022 to May 2023 were selected. The patients were divided into observation group and control group based on the Reflux Symptom Index (RSI) score filled out by the patients and the Reflux Finding Score (RFS) score filled out by the same physician. The observation group included 50 cases with RSI＞13 and/or RFS＞7, and a disease course of more than 3 months. The control group included 50 cases with RSI≤13 and RFS≤7, and no significant discomfort symptoms in the pharynx and throat in the past 3 months. Both groups underwent electronic nasopharyngolaryngoscopy, with initial examination using normal white light mode followed by switching to narrow-band imaging (NBI) mode.Results Compared with the control group, patients in the observation group showed more prominent lingual tonsillar hypertrophy and more severe inflammation, with statistical significance in both comparisons (P＜0.05).Conclusion Patients with laryngopharyngeal reflux disease exhibit more pronounced and severe inflammatory changes in the lingual tonsils