Objective To explore the therapeutic effect of ceramic rod stent implantation and platelet rich plasma (PRP) on early osteonecrosis of the femoral head (ONFH). Methods 30 patients with early ONFH from January 2021 to October 2022 in our hospital were selected, all of whom were treated with ceramic rod stent implantation combined with PRP. Record the operation time, blood loss and complications of patients, and compare the clinical efficacy ［Reconstruction Hip Scores (RHS)］, quality of life ［MOS 12 item Short Form Health Survey (SF 12)), pain degree (Visual Analog Score (VAS)］, and imaging return visit results before and 2 months after treatment. Results The incisions of 30 patients with early ONFH healed in one stage and the operation was successfully completed. The operation time was 1.92-3.33 h (2.36 ± 0.47) h, and the intraoperative blood loss was 50-267 mL (68.57 ± 10.25) mL. No infection, trochanteric bursitis, fracture and other complications occurred in all patients during and after the operation. After treatment, the excellent and good rate of RHS score (83.33%) and score grade were significantly higher than those before treatment (10.00%)（χ2=32.411，Z=32.943，P＜0.05）. SF-12 score of ONFH patients after treatment was significantly higher than that before treatment, and VAS score was significantly lower than that before treatment (t=7.937, 11.119, P＜0.05). After operation, X-ray, MRI, CT and other imaging techniques showed that the implanted ceramic rods were in good fusion condition, the hip joint performance was relatively stable, and femoral head necrosis did not progress further, and the lesion area was reduced. Conclusion The ceramic rod scaffold has the advantages of ideal mechanical strength, good hydrophilicity, being degradable and absorbed by human body, and high porosity. PRP is an autologous platelet concentrate containing a large number of growth factors. The application of ceramic rod stent implantation combined with PRP in the early ONFH treatment has significant clinical effect, high hip preservation score, and can effectively improve the pain degree and quality of life of patients, which is worthy of clinical promotion