Objective This study aimed to screen the risk factors of feeding intolerance during early enteral nutrition from the early clinically common test indexes of Severe Wasp Sting patients, and then construct an early predictive scoring model. Methods The clinical data from 119 severe wasp sting patients who were admitted at Intensive Care Unit （ICU） of 3201 Hospital of Xian Jiaotong University Health Science Center, and three designated treatment institutions for severe wasp stings in southern Shanxi, for over 96h from May 2020 to May 2023 and conformed to the inclusion criteria were retrospectively analyzed. The incidence of feeding intolerance was used as the prognosis observational index to evaluate whether the early clinically common test indexes and scoring systems were the independent risk factors for severe wasp sting complicated with feeding intolerance during early enteral nutrition. The univariate regression analysis and two-way stepwise strategy in the multivariate logistics regression model were used to select the risk factors for predicting the occurrence of feeding intolerance. According to the predicted factors, the regression equation was obtained. A visual nomogram was established using R language sofeware, and the efficacy of the nomogram was assessed by a Receiver Operating Characteristic (ROC) curve. Results The univariate regression analysis results indicated that, the influencing factors were number of stings, intra-abdominal pressure, Acute Physiology and Chronic Health Evaluation, lactate, procalcitonin and C-reactive protein (P＜0.05). Further two-way stepwise strategy in the multivariate logistics regression analysis indicated that, number of stings (OR=1.630，95%CI：1.018～1.175，P=0.006), the C-reactive protein(OR=1.107，95%CI：1.023～1.199，P=0.012) were the independent risk factors for severe wasp sting complicated with Feeding Intolerance During Early Enteral Nutrition. ROC curve analysis results showed that This nomogram has excellent predictive power for severe wasp sting complicated with feeding intolerance during early enteral nutrition(AUC=0.984, 95%CI: 0.965～1.000). Conclusion Number of stings, C-reactive protein are the main risk factors for severe wasp sting complicated with feeding intolerance during early enteral nutrition. The nomogram we constructed with these parameters can predict the risk of Feeding Intolerance early, effectively and conveniently, and have high value in clinical practical promotion and application