Objective To develop a prediction nomogram for the occurrence of abdominal aortic calcification (AAC) in patients on maintenance hemodialysis with arteriovenous fistula (AVF) using common clinical data. Methods A total of 175 maintenance hemodialysis patients from our hemodialysis centre from January 2019 to October 2022 were selected and divided into two groups (AAC group and non-AAC group) based on whether they had abdominal aortic calcification (AAC), and general information and relevant laboratory test information were collected from all patients to construct a prediction nomogram. Results A total of 175 patients were included, of which 140 were in the AAC group. The results of the comparative analysis of clinical characteristics between the two groups suggested that blood pressure, duration of dialysis maintenance, haemoglobin (Hb) and hematocrit (HCT) were higher in the AAC group than in the non-AAC group (p<0.05). A prediction nomogram for the occurrence of AAC was constructed based on Lasso regression analysis screening for age, suffering from diabetes, body mass index (BMI), diastolic blood pressure, duration of maintenance dialysis, Hb, parathyroid hormone (PTH), albumin (Alb), and total iron binding capacity (TIBC). The area under receiver operating characteristic curve (ROC) was 0.84 ［95% CI(0.76, 0.89)］, and the model precision was 0.96. The decision curve analysis (DCA) suggested that the model could increase the degree of patient benefit, and the calibration curve (CA) suggested that the model predicted results were in good agreement with the actual results. Conclusion In this study, a prediction nomogram for the occurrence of AAC in maintenance haemodialysis patients with AVF is constructed based on Lasso regression screening of predictor variables, which has good precision and discrimination and provides a reference basis for the management of vascular calcification in maintenance haemodialysis patients