To explore the application value of nasal function measurement combined with Paranasal sinus tomography (CT) imaging evaluation in the evaluation of chronic sinusitis. Methods The data of 106 patients diagnosed with chronic sinusitis in the department of Otolaryngology, Guangdong Hospital of Traditional Chinese Medicine from January 2018 to December 2020 were retrospectively analyzed, and the measurement results of nasal acoustic reflex and nasal resistance were recorded. The GOSS score and LM score were statistically analyzed by SPSS23. 0 software. Results LM score and GOSS score of patients with chronic sinusitis with nasal polyp were higher than those without nasal polyp, and the difference was statistically significant. In the measurement of nasal function, the values of V6 and V2-5 on the nasal side of nasal polyp were lower than those on the nasal side without nasal polyp, and the difference was statistically significant. There were no significant differences in nasal resistance, nasal acoustic reflection V3, MAC and MD. Spearman correlation analysis showed that there was a negative correlation between the left nasal resistance and the left nasal acoustic reflection, V6 and V2-5. There was no significant correlation between the left nasal resistance, V3, MAC and MD. There was a negative correlation between the right nasal resistance, V6, V2-5, V3, MAC and MD. There was positive correlation between GOSS score and LM score. There was no significant correlation between nasal resistance and GOSS score and LM score. Conclusion Both measurement of nasal function and imaging assessment can reflect the severity of the patient's condition to a certain extent, but with certain limitations. Combined measurement of nasal function with imaging assessment is more effective in determining the severity of chronic sinusitis, which is beneficial to preoperative assessment and prognosis prediction.