Dandy discovered the classical circulatory pathway for cerebrospinal fluid production, movement and absorption,a theory that has been recognized for nearly 100 years. In recent years, with the advancement of molecular biology detection methods and technologies, breakthrough discoveries have been made from anatomical to genetic levels in the production, movement, and absorption of cerebrospinal fluid. The discovery of meningeal lymphatic vessels provides a new pathway for the absorption of CSF/metabolites. The emergence of the lymphoid system provides a new perspective for the production and absorption of CSF in the brain parenchyma. The regular movement of cilia is an important factor in the normal circulation of CSF. The discovery and confirmation of genes related to the production of hydrocephalus provide a new theoretical basis for cerebrospinal fluid circulation disorders. Inflammation-related pathogenic microorganisms, inflammation-related cells, and factors, immune-related cells and factors, etc. and contribute new ideas for the production and absorption of cerebrospinal fluid. These new discoveries are a great challenge to traditional theories, and may also be the amendment, supplement, and perfection of the classic cerebrospinal fluid circulation. This article provides a comprehensive review of issues related to cerebrospinal fluid circulation, highlighting new findings and perspectives in recent years.