Nonfunctioning pituitary adenomas (NFPAs) are common benign tumors in the sellar area without excessive hormone secretion, Its pathogenesis is unclear. Most NFPAs are macroadenomas and can invade outside the sella, so they present with symptoms such as vision loss, visual field defect, headache and hypofunction of the anterior pituitary gland due to the tumor oppressing the visual pathway, cavernous sinus or endocranium and pituitary gland. Longterm hormone deficiency can lead to other system complications, seriously endanger the quality of life of patients, and even increase the risk of death. Clinical intervention and longterm followup management are necessary. This article presents a review about the research progress on the surgery, radiation, drug treatment and prognosis of NFPAs in order to provide reference and guidance for clinical treatment.