Objective To study image beautification of liver threedimensional reconstruction effect on laparoscopic localization of small liver cancer. Methods A retrospective analysis of 3D reconstruction cases in the second ward of General Surgery Department of Air Force Military Medical University from May 2021 to June 2022 was performed. Referring to CT and MRI film sources, a total of 14 subcapsular liver cancer nodules in 12 cases were included in the study after screening. The 14 liver cancer nodules were located as follows: 2 in S8 segment, 3 in S6 segment, 1 in S5 segment, 5 in S4 segment, 2 in S3 segment, and 1 in S1 segment. Digital medical engineers or surgeons perform 3D liver reconstruction, and the 3D reconstructed images are regarded as the image group, and the real conditions explored during the operation are regarded as the operative field group. Digital medical engineers or surgeons perform 3D liver reconstruction, and the 3D reconstructed images are regarded as the image group, and the real conditions explored during the operation are regarded as the operative field group. The reconstruction of image group and operation field group, engineer group and operator group were compared and analyzed.Results Some lesions in the image group did not correspond to the actual situation (500% vs929%), and there was a statistical difference between the image group and the surgical field group (P=0033). There was no statistical difference between the engineer and the surgeon in the threedimensional reconstruction (P＞005), but the threedimensional image reconstructed by the surgeon was more realistic (833%vs25%).Conclusion When we apply 3D reconstruction images, it is equally important to refer to CT and MRI 2D images. The engineer or radiologists who performs the reconstruction should work with the surgeon to achieve aesthetic and practical purposes in order to achieve aesthetic and practical purposes.