MRI-DWI与DCE-MRI对眼眶肿瘤的诊断价值对比
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山东省医药卫生科技发展计划(SD201901029)


Comparison on the diagnostic value of MRI-DWI and DCE-MRI for orbital tumors
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    摘要:

    目的 对比磁共振弥散加权成像(MRI-DWI)与动态增强磁共振成像(DCE-MRI)对眼眶肿瘤的诊断价值。方法 收集聊城市眼科医院2019年6月~2020年12月80例眼眶肿瘤患者的临床资料,分为良性组(n=23)和恶性组(n=57)。比较两组MRIDWI参数、DCEMRI参数。以病理结果为金标准,分析MRIDWI、DCEMRI诊断眼眶肿瘤的效能。结果 恶性组表观扩散系数(ADC)低于对照组,恶性组血管外细胞外间隙百分比(Ve)、速率常数(Kep)、容积转换常数(Ktrans)高于良性组(P<0.05);两组时间信号曲线(TIC)分型比较差异有统计学意义(P<0.05)。MRI-DWI、DCE-RI诊断眼眶肿瘤的准确度、特异度、灵敏度、阳性预测值、阴性预测值比较,差异无统计学意义(P>0.05)。〖HTH〗结论 〖HTK〗MRI-DWI、DCE-MRI均可有效诊断眼眶肿瘤,临床应综合评估量化指标及图像,以提高诊断准确度。

    Abstract:

    Objective To compare the diagnostic value of magnetic resonance imaging diffusion weighted imaging (MRI-DWI) and dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) for orbital tumors. Methods The clinical data of 80 patients with orbital tumors in Liaocheng Eye Hospital were collected between June 2019 and December 2020. They were divided into benign group (n=23) and malignant group (n=57). MRI-DWI and DCE-MRI parameters were compared between the two groups. Taking pathological results as the golden standard, diagnostic efficiency of MRI-DWI and DCE-MRI for orbital tumors was analyzed. Results The apparent diffusion coefficient (ADC) in malignant group was lower than that in benign group, while extravascular extracellular volume fraction (Ve), rate constant (Kep) and volume transfer constant (Ktrans) were higher than those in benign group (P<0.05). The differences in time-intensity curve (TIC) classifications between the two groups were statistically significant (P<0.05). The difference in accuracy, specificity, sensitivity, positive predictive value and negative predictive value for the diagnosis of orbital tumors between MRI-DWI and DCE-MRI was not statistically significant (P>0.05). Conclusion Both MRI-DWI and DCE-MRI can effectively diagnose orbital tumors. Clinically, quantitative indexes and images should be comprehensively evaluated to improve diagnosis accuracy.

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  • 在线发布日期: 2022-08-19
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