去骨瓣减压术在重型颅脑损伤中的应用进展
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The application progress of decompressive craniectomy in severe traumatic injury
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    摘要:

    【摘要】 创伤性脑损伤(TBI)是世界范围内的公众健康和社会经济问题。重型颅脑损伤后常出现颅内压(ICP)升高,进而导致脑灌注压(CPP)、脑血流量和氧合降低。这些效应会进一步加重脑水肿,形成恶性循环,严重致脑疝和死亡。去骨瓣减压术(DC)是一种去除部分颅骨并打开下方硬脑膜的手术,为不断肿胀的脑组织提供额外的空间,从而降低TBI患者ICP升高和脑疝风险。尽管DC提高了生存率,但更高比例的DC幸存者经历了中重度残疾。DC相关残疾引发了激烈的伦理争议,并且DC及随后的颅骨成形术与许多并发症有关。本文就DC重型颅脑损伤的应用进展做一综述,为重型颅脑损伤的诊疗与DC的选择提供帮助。

    Abstract:

    【Abstract】 Traumatic brain injury (TBI) is a worldwide public health and social economic problem. After severe traumatic brain injury,Intracranial pressure (ICP) often increases,leading to decreased Cerebral perfusion pressure (CPP),Cerebral blood flow and oxygenation. These effects further aggravate cerebral edema,creating a vicious cycle that can lead to severe herniation and death. Decompressive craniectomy (DC) is a procedure to remove part of the skull and open up the underlying dura mater to provide extra space for swelling brain tissue,thereby reducing the risk of elevated ICP and cerebral hernia in TBI patients. Although DC improves survival,a higher proportion of DC survivors experience moderate to severe disability. Related disabilities of DC have aroused intense ethical debate. DC and subsequent cranioplasty have been associated with many complications. In this paper,the application progress of DC in severe traumatic brain injury was reviewed,in order to provide help for diagnosis and treatment of severe traumatic brain injury and selection of DC.

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  • 在线发布日期: 2022-06-20
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