Objective To explore the images characteristics of transvaginal color Doppler sonography (TVCDS) and changes of hemodynamic parameters in patients with cervical cancer，and analyze the application value of TVCDS and changes of hemodynamic parameters in the clinical diagnosis of cervical cancer. Methods A total of 110 patients with cervical cancer admitted to the hospital from January 2018 to January 2021 were enrolled as cervical cancer group，while other 97 healthy volunteers undergoing physical examination during the same period were enrolled as control group. All underwent TVCDS. The image characteristics of TVCDS and hemodynamic parameters between cervical cancer group and control group，the image characteristics of TVCDS and changes of hemodynamic parameters among patients with different blood flow signal grading in cervical cancer group were compared. The correlation between blood flow signal grading and hemodynamic parameters was analyzed. Results The image characteristics of TVCDS in patients with cervical cancer were mainly characterized by increased anterior and posterior diameters of the cervix，and changes in contour. The echo was mainly on lowecho，there was equal echo or highecho. CDFI showed that there were abundant blood flow signals in lesion area. The proportions of rather large cervix，lowecho and highecho in cervical cancer group were significantly higher than those in control group，RI level was significantly lower than that in control group，PSV and EDV were significantly higher than those in control group (P<0.05). There were statistically significant differences in hemodynamic parameters among patients at different clinical stages and with different blood flow signal grading (P<0.05). Correlation analysis showed that RI was significantly negatively correlated with blood flow signal grading，while PSV and EDV were significantly positively correlated with it (P<0.05). Conclusion TVCDS is of high value in detecting hemodynamic parameters of cervical cancer. Hemodynamic parameters are related to clinical stage and blood flow signal grading. The evaluation on images characteristics of TVCDS and changes of hemodynamic parameters in patients with cervical cancer can provide certain guidance significance for clinical diagnosis and treatment of cervical cancer.