Objective To detect the vascular structure characteristics of cerebral arteriovenous malformation (AVM) by head imaging, and to explore the related risk factors of cerebral arteriovenous malformation with epilepsy.Methods A retrospective analysis of 107 patients with cerebral AVM admitted to Meizhou People’s Hospital was performed. Single factor correlation analysis and multiple logistic regression model were used to analyze age, gender, malformed vessel size, location, number of blood supply arteries, number of draining veins, bleeding and combined aneurysms The correlation and contribution of factors such as vein tumors to the occurrence of combined epilepsy. Results Univariate analysis found that the occurrence of AVM with epilepsy was the same age (P=0.167), gender (P=0.286), AVM size (P=0.524), location (P=0.076), number of blood supply arteries (P=0.42). There was no statistical correlation between combined bleeding (P=1.00) and combined cerebral arteriovenous tumors (P=1.00), combined smoking (2=0.482, P=0.452), combined drinking (2=0.162, P=0.596), Was significantly correlated with the number of draining veins (P=0.018). Logistic regression analysis found that for every increase in the number of draining veins, the risk of brain AVM with epilepsy increased by 1-2 times. Twenty-two patients (81.5%) were treated with one anti-epileptic drug, 3 patients (11.1%) were treated with two anti-epileptic drugs, and 2 patients (7.4%) were treated with three antepileptic drugs. Among all drugs, phenytoin sodium was the most used: 19 cases (70.4%), followed by carbamazepine: 4 cases (14.8%), and sodium valproate: 1 case (3.7%). All the prescribed dosages for all patients are made by specialists in the Department of Neurology. Through follow-up, after treatment with antiepileptic drugs, 20 patients(74.1%) did not have seizures after treatment; 3 patients (11.1%) continued to have 1 or fewer seizures per year; 4 patients (14.8%) Attack occurs once a week to a month. 〖WTHZ〗Conclusion The number of drainage veins is an independent risk factor for cerebral AVM with epilepsy.