【Abstract】Objective The clinical characteristics and related risk factors of gastric polyps were analyzed to provide basis for the prevention, diagnosis and treatment of gastric polyps.Methods 15,312 patients admitted to the Second Affiliated Hospital of Zhengzhou University from January 2014 to December 2019 were selected, including 1,424 patients with gastric polyps found under gastroscopy and 13,888 patients without gastric polyps. Relevant clinical data of the two groups of patients were collected to analyze the clinical characteristics and related risk factors of gastric polyps.Results The detection rate of gastric polyps by gastroscopy in hospital was about 9.3%, which was more common in women aged 4060 years. Most gastric polyps are single polyps, and the common pathological types are gastric fundus polyps, hyperplastic polyps, inflammatory polyps and adenomatous polyps in turn. The diameter of gastric polyps is usually ＜5mm, mostly located in the gastric fundus and gastric body. There were differences in gender, age, hyperlipidemia, hypertension, diabetes, gastric mucosa atrophy, smoking and alcohol consumption between the gastric polyp group and the nonpolyp group (P＜005), and no significant differences in the presence or absence of Hp infection (P＞005). Stepwise logistic regression analysis showed that the risk factors related to gastric polyps were female, smoking, alcohol consumption, gastric mucosal atrophy, diabetes, and advanced age (OR＞1).Conclusion Gastric polyps are more common in people over 40 years old, and are more common in women. The pathological type is gastric fundus polyps, which are more common in single occurrence and with normal diameter ＜5 mm. The risk of gastric polyps increases with age, and routine gastroscopy is recommended for highrisk groups older than 40 years.