不同方式治疗Ⅰ-Ⅱ型剖宫产术后子宫瘢痕妊娠的疗效对比
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四川省医学会医学科研课题(S18025);白求恩转化医学科研基金项目(ZHYX201812009)


Comparison of the curative effect of different treatment on cesarean scar pregnancy of type Ⅰ and type Ⅱ
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    摘要:

    目的 比较单纯宫腔镜手术、聚焦超声消融(FUA)联合宫腔镜手术、子宫动脉栓塞(UAE)联合清宫治疗Ⅰ、Ⅱ型剖宫产术后子宫瘢痕妊娠(CSP)的临床疗效及远期预后。方法 回顾性分析2016年6月~2020年5月遂宁市中心医院收治的Ⅰ、Ⅱ型CSP并接受单纯宫腔镜手术、FUA联合宫腔镜手术、UAE联合清宫术治疗的90例患者的临床资料及远期预后。结果 90例患者中,32例接受单纯宫腔镜治疗,42例接受FUA结合宫腔镜手术治疗,16例〖JP〗接受UAE结合清宫治疗。单纯宫腔镜组、FUA联合宫腔镜组、UAE联合清宫组术中出血量分别为(72.50±52.49)mL、(34.64±28.93)mL、(56.56±46.03)mL。3组术中出血量比较,差异有统计学意义(P<0.05)。3组术后月经无明显变化比率分别为43.8%、81.0%、31.3%,差异亦有统计学意义(P<0.05);FUA治疗后的NRS疼痛评分显著低于UAE组(P<0.05)。结论 单纯宫腔镜、FUA联合宫腔镜、UAE联合清宫均能安全有效用于Ⅰ、Ⅱ型CSP的治疗。但FUA联合宫腔镜治疗CSP具有出血量更少、疼痛轻、远期月经恢复好的优势。

    Abstract:

    Objective To compare the clinical efficacy and longterm outcomes of hysteroscopic surgery, focused ultrasound ablation (FUA) combined with hysteroscopic surgery, uterine artery embolization (UAE) combined with suction curettage in the treatment of cesarean scar pregnancy of type Ⅰ and typeⅡ. Methods The clinical data and long-term outcomes of 90 patients diagnosed as type Ⅰ and type Ⅱ CSP in Suining Central Hospital from June 2016 to May 2020 were retrospectively analyzed. Results Among the 90 cases, 32 cases received hysteroscopic surgery alone, 42 cases received FUA combined with hysteroscopic surgery, and 16 cases received UAE combined with curettage under guidance of hysteroscopy. The bleeding during the procedure of hysteroscopic surgery in the three groups was 72.50±52.49mL, 34.64±28.93mL, and 56.56±46.03mL respectively. A significant difference was observed among the three groups (P<0.05). The rates with no significant changes in postoperative menstruation in the three groups were 43.8%, 81.0%, and 31.3% respectively. A significant difference was observed among the three groups (P<0.05). The VAS pain score in the patients treated with FUA treatment was significantly lower than that of patients treated with UAE (P<0.05). No major complication was observed in any patient in this study. Conclusion Either hysteroscopic surgery, FUA combined with hysteroscopic surgery, and UAE combined with hysteroscopic surgery can be safely and effectively used in the treatment of typeⅠand type ⅡCSP. However, it seems that FUA combined with hysteroscopic surgery had less bleeding and pain and better longterm menstrual recovery.

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  • 在线发布日期: 2021-04-01
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