Abstract:Objective To investigate the correlation between vitamin D and left ventricular function and Framingham score in elderly patients with essential hypertension. Methods 501 elderly patients with essential hypertension from January 2018 to December 2019 in Department of Cardiology, The Affiliated Hospital of Chengdu University of Traditional Chinese Medicine were selected as the research objects. According to the serum vitamin D level, they were divided into vitamin D sufficient group (n=144), vitamin D insufficient group (n=232) and vitamin D deficiency group (n=125). The course of hypertension, smoking history, blood pressure, body mass index (BMI), serum cholesterol (TC), high density lipoprotein (HDL-C) and fasting blood glucose (FBG) were collected. The left ventricular systolic and diastolic function was evaluated by transthoracic echocardiography. The 10year risk score and risk stratification of cardiovascular and cerebrovascular events were assessed by Framingham score (FRS).Results Among the three groups, the percentage of women in vitamin D deficiency group was the highest. In vitamin D deficiency group, the percentage of smokers, BMI, DBP, SBP, TC and LDL in serum were the highest, while the HDL concentration was the lowest (P<0.05). Among the three groups, the left ventricular LVEF was the lowest, the left ventricular mass index (LVMI), IVSD, LVDD and LVPW were the highest in vitamin D deficiency group, and the percentage of abnormal E/a ratio in the group was the highest (P<0.05). Multiple linear regression analysis showed that vitamin D was still an independent risk factor for IVSD, LVDD, LVPW, LVMI, LVEF and E/a ratio (all P<0.05). FRS was the highest in vitamin D deficiencygroup, followed by vitamin D deficiency group, and lowest in vitamin D sufficient group (P<0.05). In the 10 year cardiovascular event assessment model, the percentage of lowrisk population in vitamin D sufficient group was the highest, that in vitamin D deficiency group was the highest, and that in vitamin D deficiency group was the highest (P<0.05).Conclusion The plasma levels of vitamin D is correlated with left ventricular function in elderly patients with essential hypertension. The 10year cardiovascular risk score and cardiovascular risk stratification in vitamin D deficient group are significantly higher among the three groups.