【Abstract】Objective Ultra fast pulse wave (uFPWV) was used to quantitatively evaluate carotid artery elasticity, and the correlation between atherosclerosis risk factors and agerelated arterial elasticity decline was analyzed.Methods407 subjects (214 males and 194 females, aged 19 to 86 years old (mean 536±144 years old) underwent ufPWV testing in our hospital from August 2017 to May 2018 were included. The ufPWV technology was used to measure each subject’s carotid intimamedia thickness(cIMT), pulse wave velocitybeginning of systole(PWVBS) and pulse wave velocityend of systole(PWVES). The changing trends between cIMT, PWVBS and PWV ES and the above agerelated correlation was analyzed. The influence of atherosclerosis risk factors on arterial elasticity recession was also discussed.Results There were significant differences between the male group and the female group in age, highdensity lipoprotein cIMT, PWVBS, PWVES,etc(all P＜005). There were no significant differences between the male group and the female group in the body mass index, low density lipoprotein cholesterol and triglycerides(all P＞005). PWVES(r=0650, P＜0001) was significantly better in their relevance than PWVBS(r=0222, P＜0001) and cIMT (r=0604, P＜0001) with correlation analysis with age. The regression analysis of PWVES and age in the overall population showed that the rising trend (β=0099) was significantly higher than that after excluding the related risk factors of atherosclerosis (diabetes, hypertension, hyperlipidemia, etc) (β=0079).Conclusion ufPWV technology and its parameter index such as PWVES are reliable methods for quantitative evaluation of carotid agerelated elastic recession, and the risk factors of atherosclerosis can significantly promote the development of carotid elasticity decline and atherosclerosis.