【Abstract】 Objective To explore the value of lowdose chest CT examination for screening COVID19 in hospitalized patients. Methods 216 patients underwent chest CT screening for COVID-19 before entering the hospital from February 10 to February 26, 2020 were recruited. They were randomly divided into experimental group and control group with 108 cases in each group. In the experimental group, the chest lowdose CT technique was used, and the tube voltage was 80 kV. In the control group, the conventional parameters were examined by chest CT, and the tube voltage was 100 kV. CT value, image noise, SNR, CNR, subjective score and radiation dose index, including CT dose index (CTDIvol), dose length product (DLP) and effective dose (ED), were measured, calculated and compared. Results There weresignificant differences in CT value, image noise, SNR, CNR, subjective score, CTDIvol, DLP and ED between the two groups (P＜0.05). The image noise of the experimental group was higher than that of the control group (P＜0.05). The SNR, CNR, subjective score, CTDIvol, DLP, ed of the experimental group were lower than those of the control group (P＜0.05). The subjective scores of the two groups were higher than 3, which could meet the diagnostic requirements. Conclusion In COVID-19 patients screening, the low dose CT examination can not only meet the diagnostic needs, but also effectively reduce the radiation dose received by patients during the examination. It has high clinical value and is worth learning from. 