【Abstract】 Objective To explore the relationship between serum ferritin, CD4+ T cells, CD8+ T cells and abdominal aortic calcification scores in patients undergoing maintenance hemodialysis. Methods 100 patients undergoing maintenance hemodialysis and 52 healthy individuals completing health checkups in the hospital during the period from September 2017 to September 2019 were selected as the study group (n=100) and the control group (n=52). The levels of serum ferritin, CD4+ T cells and CD8+ T cells, and abdominal aortic calcification scores were measured. Patients in the study group were divided into the calcification group (n=47) and the noncalcification group (n=53) according to the abdominal aortic calcification score. The levels of serum ferritin, CD4+ T cells and CD8+ T cells, and abdominal aortic calcification scores in the three groups were compared. The correlation between serum ferritin, CD4+ T cells, CD8+ T cells and abdominal aortic calcification scores was analyzed, and the incidence rates of adverse cardiovascular events in the three groups were recorded. The value of above indexes in predicting adverse cardiovascular events was analyzed. Results The scores of serum ferritin, CD4+ T cells and abdominal aorta calcification in calcified and non calcified groups were higher than those in control group, and CD8+ T cells were lower than those in control group (P＜0.05). The scores of serum ferritin, CD4+ T cells and abdominal aorta calcification in calcified group were higher than those in non calcification group, while CD8+ cells in calcified group were lower than those in non calcification group (P＜0.05). Pearson correlation analysis showed that serum ferritin and CD4+ T cells were positively correlated with abdominal aortic calcification score (r=0.446, 0.521, P＜0.05), while CD8+ T cells were negatively correlated with abdominal aortic calcification score (r=-0624, P＜0.05). The incidence of adverse cardiovascular events was 57.45%, 33.96% and 1.92% in calcified group, non calcified group and control group, respectively. There was significant difference among the three groups (P＜0.05). ROC curve showed that the AUC of serum ferritin, CD4+ T, CD8+ T cells and abdominal aortic calcification score in predicting adverse cardiovascular events were 0.612, 0.772, 0.732 and 0.803, respectively. Conclusion Serum ferritin, CD4+ T cells and CD8+ T cells are closely related to abdominal aortic calcification scores in patients undergoing maintenance hemodialysis, which can be used to predict the occurrence of adverse cardiovascular events.