Abstract:Objective To evaluate safety and effectiveness of Percutaneous kyphoplasty (PKP) in patients with spinal metastases with posterior wall defects. Methods 32 patients with vertebral metastases with posterior edge destructionreceived PKP treatment in our hospital from December 2016 to June 2019 were selected as the research objects. Oswestry disability index (ODI) was used to measure the severity of dysfunction, and the pain digital score (NRS) was used to measure the degree of pain. The changes of dysfunction and pain before and after PKP treatment and the efficacy of PKP were analyzed. The safety of PKP was evaluated by observing whether serious complications occurred during and after PKP.Results In 32 patients, 37 vertebral metastases with bone destruction at the posterior edge were treated with PKP. Compared with 1 day before operation, ODI and NRS scores were significantly improved at 3 days, 1 month,3 months and 6 months after operation (P<0.05). No serious complications occurred during and after operation.Conclusion PKP can significantly relieve the pain and improve the quality of life of patients with vertebral metastases with posterior edge destruction. It can be used as a minimally invasive, safe and effective surgical method in clinical practice.