Abstract:Objective To explore the characters and influencing factors of abnormal left ventricular geometry in patients with central obesity and hypertension and provide ideas for the prevention and treatment of heart damage in obesityrelated hypertension.Methods 227 patients with central obesity complicated with hypertension from May 2015 to February 2016 in our hospital were enrolled. The general data, inflammatory factors, early renal damage index, uric acid, B-type natriuretic peptide (BNP), cardiac ultrasound were collected. According to the characteristics of echocardiography, the patients were divided normal configuration, concentric remodeling, centrifugal hypertrophy and concentric hypertrophy. The risk factors of left ventricular geometric disorder were analyzed by unconditional logistic regression.ResultsAmong 227 patients, 58 (25.55%) had normal configuration, 99 (43.61%) had centripetal remodeling, 44 (19.38%) had concentric hypertrophy and 26 (11.45%) had eccentric hypertrophy. Among them, 74.45% of them had left ventricular remodeling disorder. Unconditional logistic regression analysis showed that the level of high sensitivity C-reactive protein (hsccrp) increased (R=1.591, 95% CI=1.185~2.073), blood pressureclassification increased(OR=1.611, 95%CI=1.008~2.575), BNP increased (OR=1.408, 95%CI=1.064~1.863), age increased (OR=1524, 95%CI=1.185~2.073), blood pressure classification increased (OR=1.611, 95% CI=1.008~2575), BNP increased (OR=1.408, 95%CI=1.064~1.863), age (OR=1.524, 95%C=1.064~1.863), age (OR=1.524, 95%CI=1.524, 95% CI=1.524, 95%CI=1.054~2.203) increased the center The risk of left ventricular geometry disorder in obese patients with hypertension.Conclusion 74.45% of patients with central obesity complicated with hypertensionhad left ventricular remodeling. With the increase of hsCRP, age, BNP and blood pressure grade, the risk of left ventricular geometry disorder is also increased in patients with central obesity and hypertension.