Objective To compare glycolipid metabolism and follicular fluid T, IGF-1 in PCOS patients with different testosterone levels in Inner Mongolia. Methods From July 2017 to December 2018, 198 PCOS patients of Han nationality who received IVF ET assisted pregnancy treatment in our hospital were selected as the study objects. According to the serum testosterone level, they were divided into the observation group (serum testosterone ≥ 70 ng/dl, n=45) and the control group (serum testosterone <70 ng/dl,n=153). The medical history and physical examination were collected. On the 2nd to 5th day of menstruation, blood was drawn on an empty stomach to detect sex hormone, blood glucose and blood lipid. PCOS patients with infertility were treated with IVFET, and follicular fluid was collected on the day of oocyte collection. T and IGF 1 levels of follicular fluid were measured. The clinical data, serum and follicular fluid indexes and clinical outcomes of the two groups were analyzed and compared.Results BMI, LH/FSH (L/F), fasting blood glucose (FPG), fasting insulin (fins), cholesterol (CHO), triglyceride (TG), low density lipoprotein (LDL), apolipoprotein A (ApoA) in the observation group were higher than those in the control group, but the difference was not statistically significant (P>0.05). The rate of MII eggs and the rate of excellent embryos were significantly lower than that of the control group. The incidence of IR and dyslipidemia, the level of T and IGF 1 in serum and follicular fluid were significantly higher than that of the control group (P<0.05).Conclusion The hyperandrogen state in PCOS patientsof Han nationality in Inner Mongolia is prone to abnormal glucose and lipid metabolism, and the level of T and 〖JP2〗IGF 1 in follicular fluid is likely to rise, which affects the quality of oocytes, and is related to the clinical outcome of IVF ET.