【Abstract】Objective To explore the value of angiopoietinlike protein 2 (Angpt2), angiopoietinlike protein 1 (Angpt1) and highsensitivity troponin T (hscTnT) in predicting major adverse cardiovascular events (MACE) in angina patients undergoing percutaneous coronary intervention (PCI). Methods A total of 123 angina patients underwent PCI in Yibin Second People's Hospital from March 2015 to May 2018 were enrolled. Serum Angpt2, Angpt1 and hscTnT were compared among patients with different grades of angina. They were grouped according to the occurrence of MACE during the 1year followup. Risk factors for MACE were screened. The predictive value of above parameters for MACE in angina patients undergoing PCI, and the correlation among the three indicators were analyzed. 〖WTHZ〗ResultsWith the increase of the grade of angina, levels of serum Angpt2 and hscTnT increased, while the Angpt1 level decreased (P＜005). The levels of serum Angpt2 and hscTnT in MACE group were higher than those in nonMACE group, while the Angpt1 level was lower than nonMACE group (P＜005). The proportions of left ventricular ejection fraction (LVEF) lower than 50%, N terminal pro B type natriuretic peptide (NTproBNP) not higher than 500 pg/mL and grade III angina in MACE group were higher than those in nonMACE group (P＜005). Angpt2, hscTnT, LVEF, NTproBNP and angina grading were all risk factors for MACE after PCI (P＜005). When the Youden index of Angpt2 for predicting MACE after PCI was the largest, the sensitivity and specificity were 9565% and 7900%. When the Youden index of hscTnT was the largest, the sensitivity and specificity were 7391% and 8900%. When the Youden index of Angpt1 was the largest, the sensitivity and specificity were 6087% and 8200%. Angpt2 was negatively correlated with Angpt1 (P＜005), but positively correlated with hscTnT (P＜005). Angpt1 was negatively correlated with hscTnT (P＜005). Conclusion The occurrence of MACE in patients with unstable angina after PCI is related to changes in levels of Angpt2, Angpt1 and hscTnT. Angpt2 and hscTnT are of great value for predicting MACE after PCI while the predictive value of Angpt1 is limited. There is a correlation among the expression of the three indicators.