【Abstract】Objective To evaluate the status and prognosis of patients with abdominal infection admitted to intensive care unit (ICU) after general surgery and provide a basis for judging the severity and prognosis of patients. Methods The clinical data of 70 patients with abdominal infection after general surgery in our hospital from June 2014 to June 2017 were analyzed retrospectively. According to the outcome of transferring out of ICU, they were divided into survival group (n= 46) and death group (n=24). The general data of the two groups were recorded, including sex, age, operation site and length of stay in ICU; lac, PCT, blood routine, CRE, WBC count, NLR and PLR. 24 Acute physiology and chronic health status scoring system Ⅱ (APACHE Ⅱ) and sofa scores were performed when the disease was the most serious within H. The relationship between the condition and prognosis of patients with abdominal infection in ICU were recorded. Results There was no significant difference in age, sex composition, NLR, PLT, lac and cre between the two groups (P>005). Compared with the survival group, the leakage of intestines in the death group was significantly higher, the time of admission to ICU was significantly longer, PLR, PCT, Apache Ⅱ and sofa were significantly higher (P<005). Logistic regression analysis showed that PLR, Apache Ⅱ score and SOFA score were independent risk factors for the prognosis of patients with abdominal infection in ICU after general surgery (P<005). Conclusion pache Ⅱ score, SOFA score and PLR are independent risk factors to judge the disease severity and prognosis of patients with abdominal infection after general surgery, which can judge the outcome of patients to a certain extent.