Objective To explore the selfmanagement ability and control effect of chronic disease management model for children with asthma. Methods 200 children with asthma were enrolled in this study from June 2017 to June 2019 in our hospital and divided into study group and control group, according to the random number table method. All children were given inhaled glucocorticoid +longacting beta 2 receptor agonists. The control group was given routine care and the study group given chronic disease management model. The lung function, asthma control, and selfrating self  rating scale were compared between the two groups before discharge and at the end of the followup. Results At the end of followup, PEF%, FEV1%, 25% FEF, 50% FEF and 75% FEF increased in the two groups, but that of the study group were higher than that of the control group (P＜0.05). At the end of followup, there were 32 cases with complete control of asthma symptoms (32.00%) in the study group and 16 cases with complete control of asthma symptoms (16.00%) in the control group (P＜0.05). At the end of followup, the three dimensions and total scores of selfrating selfrating scale increased in the two groups, but that of the study group were higher than that of the control group (P＜0.05).Conclusion The self management model of chronic disease can improve the lung function of children with asthma, the control effect of children and the self management ability of children.