Functional restoration after spinal cord injury (SCI) is one of the most challenging tasks in neurological clinical practice. With a view to exploring effective neurorestorative methods in the acute, subacute ? and chronic phases of SCI, “Clinical Therapeutic Guidelines of Neurorestoration for Spinal Cord Injury (China Version 2016)" was first pro posed, in 2016 by the Chinese Association of Neurorestoratology (CANR). Given the rapid advances in this field in recent years, the International Association of Neurorestoratology (IANR) and CANR formed and approved the "Clinical Neuro restorative Therapeutic Guidelines for Spinal Cord Injury (IANR/CANR version 2019)". This guideline provided com prehensive management strategies for SCI, which contains the evaluation and diagnosis, pre hospital first aid, treat ments, rehabilitation training, and complications management. Nowadays, amounts of neurorestorative strategies have been demonstrated to be benefit in promoting the functional recovery and improving the quality of life for SCI patients by clinical trials. Also, the positive results of preclinical research provided lots of new neurorestorative strategies for SCI treatment. These promising neurorestorative strategies are worthy of translation in the future and can promote the advancement of SCI treatments. These guidelines can provide a neuro restorative therapeutic standard or reference for cli nicians and researchers in clinical practice to maximally restore functions of patients with SCI and improve their quality of life.