Abstract:【Abstract】 Objective The parameters of uterine artery blood flow in early pregnancy were observed and analyzed, and the relationship between the parameter changes and recurrent abortion and the effect on pregnancy outcome were discussed. Methods 90 pregnant women with abortion times ≥ 3 times and 6 to 10 weeks gestation were selected as observation group, and 90 pregnant women without history of adverse pregnancy were selected as control group. The bilateral uterine artery hemodynamic parameters (beating index PI, resistance index RI, arterial endsystolic peak/enddiastolic flow rate S/D) of pregnant women were monitored by vaginal ultrasound after ovulation and 6 to 10 weeks of pregnancy, respectively. The changes in blood flow parameters and the effects on pregnancy outcomes were compared between the two groups. Results The parameters of uterine artery blood flow PI, RI, S/D in the observation group were significantly higher than those in the control group, and the comparison between groups (Statistics=5477, 8.828, 8.584, P＜005), all had statistical significance. The early abortion rate of the observation group was 7556%, which was significantly higher than that of the control group (3.33%, 2=15.050, P＜0.05). The ROC curve of the subjects showed that the uterine artery blood flow parameters RI, PI, S/D had good diagnostic value for pregnancy outcomes, and the area under the curve of PI was the largest, but the differences in sensitivity and specificity were compared. Not statistically significant (P＞0.05). Logistic regression analysis showed that S/D, RI, and PI increased to high risk factors for recurrent spontaneous abortion (95% CI: 2.069-16.786, 1.255-5.114, 2.710-6.346; P＜0.05). Conclusion There are abnormalities in uterine artery blood flow parameters in pregnant women with recurrent spontaneous abortion. The higher the PI, RI, S/D index, the higher the abortion rate, and the early and effective correction of abnormal blood flow in early stage, it plays a good role in pregnancy outcome.
