Abstract:Objective To explore the value of ultrasonography in the diagnosis of fetal hypospadias.Methods From January 2011 to December 2017, 31 cases of pregnant women in the obstetrics department of Mianyang Central Hospital and Nanchong Central Hospital were analyzed retrospectively. 2DUS and 3DUS examinations were performed in sequence due to suspected hypospadias. The ultrasonic image features and missed and misdiagnosed cases of hypospadias were summarized. The occurrence rate of different sonographic features and the correct diagnosis rate of hypospadias were compared. Based on the results of labor (or induction) as the gold standard of diagnosis, the sensitivity, specificity and accuracy of the two methods were compared.ResultsA total of 31 cases were diagnosed as non hypospadias in 6 cases and hypospadias in 25 cases. The occurrence rate of "penile shortness" was high, but the specificity wass poor; while the occurrence rate of "abnormal urine spraying" and "interruption of urethral continuity" was low, but the specificity was high. Among 31 suspected cases, 22 cases were accurately diagnosed by 2DUS, 5 cases were missed and 4 cases were misdiagnosed. The sensitivity, specificity and accuracy of the diagnosis were 80.0%, 33.33% and 70.97% respectively, while 27 cases were accurately diagnosed by 2DUS with 3DUS, 3 cases were missed and 1 case was misdiagnosed. The sensitivity, specificity and accuracy of the diagnosis were 88.00%, 83.33% and 87.10% respectively. The difference between the two imaging methods was statistically significant (P < 0.05).Conclusion Ultrasonography is a reliable method for diagnosis of hypospadias. The application of 2DUS combined with 3DUS in prenatal diagnosis of hypospadias can significantly improve the sensitivity, specificity and accuracy of diagnosis compared with 2DUS alone.
