Objective During the period of Corona Virus Disease 2019 (COVID19), the psychological status of the medical staff in hemodialysis room was analyzed, and the correlation between the psychological status and social support status was also discussed. Methods The mental health and social support of 131 medical staff in West China Hospital, Sichuan University, Meishan People′s Hospital, Chengdu 7th People′s Hospital, Mianzhu People′s Hospital, Sichuan Integrated Traditional Chinese and Western Medicine Hospital were investigated by general data questionnaire, public health emergency questionnaire and perceived social support scale (PSSS). Pearson was used to analyze the correlation .Results The fear score of medical staff in hemodialysis room was (0.93±0.57). The score of neurasthenia was (0.35±0.47). The depression score was (0.29±0.41). The score of suspicious disease was (0.18±0.36). The score of obsession anxiety was (0.14±0.27). There was a significant negative correlation between perceived social support score and the mental score (62.96±11.11) (P＜0.05) .Conclusion During the COVID19, there were different degrees of mental health problems such as fear, neurasthenia, depression, compulsion anxiety in hemodialysis room staff. As for the severe epidemic diagnosis and treatment tasks, medical staff needed more social support, training in emergency knowledge and emergency and professional psychotherapy.