【Abstract】 Objective To investigate the diagnostic value of coronary CT angiography (CTA) in the degree and location of coronary heart disease. Methods From February 2016 to February 2019, 268 patients with coronary heart disease in our hospital were selected for CTA and CAG. With CAG as the gold standard, the consistency, sensitivity, specificity and accuracy of CTA in the diagnosis of coronary heart disease were compared. Results The kappa value of CT angiography in the diagnosis of moderate and severe stenosis was 0.718 and 0.803 respectively. The sensitivity, specificity and accuracy of CT angiography in the diagnosis of moderate and severe stenosis were 9570%, 94.94%, 81.82%, 92.00%, 94.23% and 94.51%, respectively. Kappa was 0.718 and 0.803 for single and multi vessel lesions respectively. The sensitivity, specificity and accuracy of single and multi vessel lesions were 97.04%, 95.15%, 83.33%, 91.67%, 95.42% and 94.78%, respectively. The kappa values of the lesions were 0.825, 0.718, 0.846, respectively. The sensitivity, specificity and accuracy of the lesions were 97.14%, 94.74%, 96.92%, 87.50%, 80.00%, 90.91%, 95.87%, 92.54%, 91.25%, respectively. Conclusion CT angiography of coronary artery has good consistency in the diagnosis of severe stenosis of coronary heart disease, single vessel disease, multi vessel disease, lesion location in anterior descending artery and right coronary artery, moderate stenosis, lesion location in circumflex artery.