【Abstract】 Objective To study the correlation between blood pressure changes and neurological deficits in acute cerebral infarction. Methods 97 patients with acute cerebral infarction were collected. They performed an ambulatory blood pressure monitoring and recording cerebral ischemic events on the second day of admission. According to the variety of the NIHSS score in monitoring of blood pressure, the patients were divided into nerve function defect with recombinant (exacerbation group) and nerve function defect no change group (no change group). Blood pressure values were divided into five groups: A:~119/~79mmHg，B:120~139/80~89mmHg，C:140~159/90~99mmHg，D:160~179/100~109mmHg，E:180~/110~mmHg. The collected blood pressure values and cerebral ischemic events were used as the research object. The main distribution of blood pressure in two groups and blood pressure interval of cerebral ischemic events lesser occurring were observed. Results The blood pressure of the exacerbation group was mainly concentrated in A and E group, while the blood pressure values in the no change group were mainly concentrated in B, C, D group, and the difference of blood pressure between the two groups was statistically significant（P＜005）. There was significant difference in the distribution of cerebral ischemic events in exacerbation group (P＜001),systolic blood pressure in the D group, diastolic pressure in the C group had the least ischemic events. cerebral ischemic events in the no change group showed no significant differences in blood pressure in each group(P＞005). Conclusions Change of blood pressure in acute phase of cerebral infarction and neurological deficit have correlation.There is a blood pressure interval 160~180/90~100mmHg that occurs cerebral ischemic events lesser. The blood pressure interval is more suitable for patients with acute cerebral infarction.