【Abstract】 Objective To compare the safety and postoperative complications of two methods of SLIPA laryngeal mask and traditional placement in general anesthesia for cesarean section. Methods 60 cases of singleton pregnancy in general anesthesia for elective cesarean section maternal, ASA grade IIor III, 28~43 years old, 62 ~ 85kg, were randomly divided into modified implantation group (G group) and the conventional implantation group (C group), 30 cases in each group. After the induction of general anesthesia, the SLIPA laryngeal mask was placed in their respective methods. The induction of general anesthesia to fetal childbirth time (ID), uterine incision to delivery time (UD), operation time and amount of bleeding were observed. The blood gas analysis of umbilical artery and vein blood were extracted from fetus. The packets of unsuspecting paediatricians, 5min and Apgar in 1min 5D and 7d NBNA score were recorded. For the first time in record time, oropharyngeal leak pressure and intraoperative continuous monitoring of noninvasive arterial pressure were recorded. The time of pulling out the laryngeal mask of arterial blood pressure and heart rate, postoperative laryngeal mask after removal of blood viscosity, reflux, aspiration, sore throat and hoarseness were observed. Results There was no significant difference in the series of data related to operation and newborn (P＞0.05). The time of ID and UD were within the safety range. The first success rate in group G was 100%, and 4 cases in group C had the second successful implantation. Compared with the G group, the hemodynamic changes at each time point of the insertion and removal of the laryngeal mask were obvious in the C group (P＜0.05). Patients in the two groups were no regurgitation and aspiration. Conclusion SLIPA laryngeal mask improved placement method can significantly improve the success rate of implantation, and airway sealing is good. It can be safely used for elective general anesthesia cesarean section, with fewer adverse reactions.