Objective To investigate the value of realtime threesection autoimaging AFI in the evaluation of longitudinal systolic function in patients with essential hypertension. Methods 60 patients with essential hypertension without left ventricular hypertrophy from May 2016 to May 2017 (group B), 60 patients with left ventricular hypertrophy (group C) and 60 healthy persons (group A) were selected in the present study. The realtime threeplane twodimensional dynamic grayscale images of left ventricular apex were recorded. The AFI software was used to detect the global systolic longitudinal strain (GLS) and local systolic peak strain (RLS) in 17 segments of the left ventricle, and the corresponding data were compared and analyzed. ResultsThe local peak strain of hypertension patients in group B and group C at different levelsbasal, middle and apical segments was lower than that of healthy group A (P＜0.05). The local peak strain in the basal segment and the middle segment was lower than that in the B group (P＜0.05). The whole peak strain value in both LAX and 2C in group B was lower than in that in group A (P＜0.05). The overall average peak strain AVg in group C was lower than that in group B. (P＜0.05). The local peak strain in group B was lower than that in group A at the systolic phase in all segments (P＜0.05). In group C, the local peak strain in the systolic phase of the anterior and posterior wall was lower than that of B in different segments.Conclusion When the left ventricular systolic function is normal in patients with essential hypertension, and the configuration did not change, the whole and local strains of the heart muscle could be reduced. Changes in global and local strain values are not statistically significant, when the configuration is changed and when the configuration is not changed. AFI technology can accurately and quantitatively assess the early and overall longitudinal systolic function changes of left ventricular myocardium in patients with essential hypertension.