Objective To investigate the effect of regular oral hygiene maintenance on the stability of dental implant in type 2 diabetic patients. Methods 158 patients with type 2 diabetes persisted in the return visit for 3 years collected from the patients undergoing dental implant surgery in our hospital were defined as diabetic group after 2013. The diabetic group was divided into three grades according to the number of times to receive oral hygiene maintenance in the three years. The same method was divided into three grades in 140 patients who were not diabetic at the same time and received dental implant surgery. The differences of sulcus bleeding index (SBI), probing depth (PD), the distance from the shoulder of the implant to the bottom of the bony defect (DSB), implant stability quotient (ISQ) and hemoglobin A1C (HbA1C) were analyzed in the third year after implant surgery. Results Comparing the control group and the diabetic group, there was a statistically significant difference in the SBI between the 56 times grade during the three years (P＜0.05). The SBI, PD, DSB, ISQ and HbA1C were significantly different in the 3-4 times grade and less than or equal to 2 times grade (P＜0.05). Comparing intragroup, the PD and DSB were significantly different between less than or equal to 2 times grade and the other grades within the control group (P＜0.05). The SBI, PD, DSB and ISQ were significantly different between each grade within the diabetic group (P＜0.05). There was a statistically significant difference in HbA1C between the grade of less than or equal to 2 times and the grade of 3-4 times and 5-6 times (P＜0.05).Conclusion Regular oral hygiene maintenance every six months after dental implant surgery in type 2 diabetic patients can significantly improve the periodontal status of implant and reduce the level of HbA1C, which is beneficial to maintain the stability of implant.