【Abstract】 Objective To investigate the relationship between the changes of serum cardiac troponin content ( cTnI) and acute cerebral hemorrhage (ACH). Methods 68 ACH patients and 50 healthy people in our hospital from January 2015 to December 2016 were included into the observation group and the control group, respectively. Enzyme linked immunosorbent assay (ELISA) was used to detect the level of serum cTnI. National institutes of health stroke scale (NIHSS) was used to evaluate neurological dysfunction. The levels of serum cTnI in patients with different levels of neurological dysfunction and different amount of blood loss were compared and analyzed. Results The serum cTnI levels after the onset of 24h, 3D, 7d, 14d in the observation group were statistically significant (P＜005); The level of serum cTnI in the observation group was significantly higher than that in the control group at each time point, and the difference was statistically significant (P＜005). There were significant differences in serum cTnI levels at different time points in patients with different levels of neurological disorders (P＜005). There were significant differences in serum cTnI levels at different time points in patients with different amount of blood loss(P＜005). Serum cTnI level was positively correlated with NHISS score and blood loss (r=0764, P＜0001, r=0654, P＜0001). Conclusion The level of serum cTnI is increased significantly in patients with ACH, which is positively correlated with neurological disorders and blood loss, so it can be used as an important indicator of early myocardial injury in patients with ACH.