老年糖尿病患者牙周指数与血脂、血糖相关性分析
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国家自然科学基金(81401598)


Correlation analysis of periodontal index, blood lipid and blood glucose in elderly patients with diabetes mellitus
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    摘要:

    【摘要】 目的 探讨牙周指数与老年糖尿病患者血糖、血脂的相关性。方法 根据是否患有牙周炎将98例老年糖尿病患者分为糖尿病+牙周炎组(n=46)和糖尿病组(n=52)。另随机选择健康人群30例为对照组。比较各组受试者血小板参数、凝血四项、血糖、血脂。比较糖尿病患者的牙周指数,并进行与血糖、血脂各指标的相关分析。结果 3组血小板参数、凝血四项、血糖、血脂比较差异具有统计学意义(P<005)。糖尿病+牙周炎组PLT、MPV明显高于对照组及糖尿病组,PT、FIB明显低于对照组及糖尿病组(P<001)。糖尿病+牙周炎组TC、TG、LDL水平明显高于糖尿病组及对照组;HDL水平明显低于糖尿病组及对照组(P<005)。糖尿病+牙周炎组龈沟出血指数(SBI)、附着丧失(AL)值高于糖尿病组(P<001)。各牙周指标与FPG、HbAlc、TC呈正相关(P<005),与HDL呈负相关(P<005);简化牙石指数(CIS)与LDL呈正相关(P<005),其余牙周指标与LDL均无相关性(P>005)。结论 牙周炎可能通过影响老年糖尿病患者血糖、血脂水平增加微血管病变风险,加重病情。

    Abstract:

    【Abstract】 Objective To investigate the correlation between periodontal index and blood glucose and blood lipid in elderly diabetic patients.Methods 96 patients with diabetes were divided into diabetic periodontitis group (n= 46) and diabetic group (n= 52). 30 healthy people were selected into control group. Compared the platelet parameters, coagulation blood, blood glucose and blood lipid in each group. The index of periodontal index of diabetic patients was compared with that of blood glucose and blood lipid. Results There was significant difference between the three groups of platelet parameters, blood clotting, blood glucose and blood lipid (P<005). The PLT and MPV of diabetic periodontitis were significantly higher than those in the control group and the diabetic group. PT and FIB were significantly lower than the control group and the diabetic group (P<001). The levels of TC, TG and LDL of diabetic periodontitis were significantly higher than those of diabetes group and control group, and the HDL level was significantly lower than that of diabetic group and control group (P<005). The SBI and AL value of diabetic periodontitis were significantly higher than that of diabetes group (P<001). The index of periodontal index has different degrees of correlation with blood glucose and blood lipid index. Conclusion Periodontitis may increase the risk of microvascular disease by affecting blood glucose and lipid levels in elderly diabetics.

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  • 在线发布日期: 2018-08-01
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