Abstract:【Abstract】Objective The aim of the study was to evaluate the safety and efficacy of early intensive and conservative BP lowering treatment in patients with hypertension cerebral hemorrhage. Methods By randomized controlled clinical trial, the clinical data of patients with hypertension cerebral hemorrhage treated from May 2014 to January 2016 were collected. The patients were randomly divided into conventional treatment group (systolic pressure control 160140mmHg) and intensive treatment group (systolic pressure control in 140120mmHg).Results 111 patients completed the trial, including the conventional treatment group (57 cases) and intensive treatment group (54 cases). There was no significant difference in the volume of hematoma (21±29 vs 29±25 ml, P=0.351) and rebleeding rate (15.8% vs 5.6%, P=0.604) in the conventional treatment group and the intensive group 48h after operation. GCS of the two groups of patients with postoperative 48h and postoperative 3 months (8.53±3.08 vs 8.00±3.27, P=0.617 and 13.05±1.99 vs 11.44±3.88, P=0.119), NIHSS (24.58±8.35 vs 23.61±9.91, P=0.749 and 7.53±5.97 vs 10.44±8.40, P=0.229), modified MRS score (4.63±0.60 vs 4.67±0.77, P=0.877 and 2.53±1.47 vs 2.89±1.61, P=0.478) had no significant difference. Conclusion For patients with hypertension cerebral hemorrhage after surgery, the use of standard antihypertensive and enhanced blood pressure are safe, the two groups of shortterm prognosis and longterm prognosis are similar.