肝硬化门静脉系统血栓的病因及治疗研究进展
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The latest development of causes and treatment in liver cirrhosis with portal venous thrombosis
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    摘要:

    【摘要】 肝硬化伴门静脉系统血栓疾病在临床上并不罕见,其临床表现多样,可导致各种并发症。按血栓发生的时间及其影像学表现可将其分期、分度和分级。其病因可能包括凝血功能及血流动力学异常等。治疗策略目前尚存争议,缺乏预防性治疗的可靠证据,对于无门静脉血栓临床症状且分级为II级或者有门静脉血栓临床症状但能够通过消化道内镜、腹腔穿刺及药物控制症状的患者,倾向于运用有临床证据的依诺肝素行抗凝治疗。对于抗凝治疗无效且进一步进展或者合并反复的上消化出血及难治性腹水的患者,目前倾向于行经颈静脉肝内门体分流术(tips)治疗。通过分析近年来发表的相关文献,本文将对其病因及治疗的最新进展作一综述。

    Abstract:

    【Abstract】 Liver cirrhosis with portal venous thrombosis (PVT) diseases is not rare in clinic. Its clinical presentation is variability and can lead to a variety of complications. According to the time and the imaging findings of the thrombus,it can be staged,degreed and classified. The causes may include blood coagulation function and hemodynamic abnormalities. The treatment strategy is still disputed, lack of reliable evidence for preventive treatment,For the absence of clinical symptoms but classified as Class II or portal vein thrombosis have symptoms but can through the digestive tract endoscopy, abdominocentesis and drugs to control the patient's symptoms, tend to have clinical evidence of the use of enoxaparin anticoagulation therapy. For anticoagulation therapy failed and further progress on the symptoms or digestive bleeding in patients with recurrent and refractory ascites, the current tends to be treated tips. Through analysing related articles published in recent years, this article will review the latest progress of its etiology and treatment.

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  • 在线发布日期: 2017-06-20
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