Abstract:【Abstract】 Objective The aim of the study was to evaluate factors that could predict the development of local complications (pleural effusion, necrotizing pneumonia) in children with community acquired pneumonia (CAP). Methods The clinical data of 101 children with pneumonia from March 2015 to March 2016 in our hospital were divided into nocomplications pneumonia group (N group) and complications pneumonia group (C group). Demographic, clinical and laboratory data were prospectively collected and compared. Univariate and multivariate analyses were performed to identify factors associated with local complications of CAP.Results The long length of hospital stay, acute inflammation, unilateral chest pain and prehospital antiinflammatory medication of C group were more common than that of N group. Children with complicated CAP had a significantly higher serum CRP concentration as well as higher WBC and neutrophil count. Antiinflammatory drugs cumulative dose were more than 752 mg/kg. The complications OR value increased 20 times (OR 202, 95% CI 141~ 564;p= 0079).Conclusion Duration of fever, chest pain, acute inflammation, especially the antiinflammatory drug treatment are associated with significant pneumonia local complications.