【Abstract】 Objective To study the effect of budesonide, promethazine supporting bromide and salbutamol in combination with oxygen atomization of patients with asthmatic pneumonia.Methods 90 patients with asthmatic pneumonia in accordance with admission number of single and double situation were divided into the observation group and the control group. The control group was treated with atomization inhalation of budesonide. The observation group was treated with atomization inhalation of budesonide, isopropyl bromide, salbutamol and combination with oxygen.The pulmonary function parameters and main symptoms disappear time were observed.Results Total effective rate of observation group was significantly higher than that of control group (P＜ 005). FEV1, FEV1% and SaO2 t of observation group were significantly higher than that of the control group (P＜005). The disappearing timeof medium crackles, cough, wheezing sound in lung inobservation group were shorten than in control group(P＜005). Conclusion The use of budesonide, promethazine supporting bromide and salbutamol in combination with oxygen atomization of patients with asthmatic pneumonia treatment can quickly reduce the original symptoms, significantly improvement in lung function and has good curative effect.