【Abstract】 Objective To investigate the value of procalcitonin (PCT) to use antibiotics in children with community acquired pneumonia (CAP). Methods〓84 children with CAP were included. The patients were divided into observation group (42 cases) and control group (42 cases) by random number table method. The observation group was based on the concentration of PCT to determine whether the use antibiotics. Control group was according to the Guiding Principles for Clinical Application of Antimicrobial Agents (2015 version) and clinical experience to use antibiotics. Data was collected on the situation of antibiotics use, antibiotic prescription usage rate, situation of after treatment, length of stay, cost of hospitalization and curative effect. Results The constituent ratio of the use of antibiotics, antibiotic use days, constituent ratio of combined use of two antibiotics, constituent ratio of adverse antibiotics reaction, antibiotic cost, length of stay and cost of hospitalization in the observation group were significantly less than those in the control group (P＜005). In the treatment of first, third, fifth days, the antibiotic prescription usage rate in the observation group was significantly lower than that in the control group (P＜005). In the observation group, the fifth days after treatment, the use rate of antibiotics was significantly decreased, while in the control group was seventh days after treatment. There was no significant difference in the curative effect and disappearance time of clinical symptoms between the two groups (P＞005).Conclusions The strategy of using PCT to guide use antibiotics in children with CAP not only does not affect the efficacy, but also can effectively reduce the use of antibiotics, adverse antibiotics reaction, antibiotic cost, course of antibiotics usage, length of stay and cost of hospitalization