【Abstract】 Objective To compare the diagnostic value of conventional ultrasonography, contrastenhanced ultrasonography (CEUS) and contrastenhanced CT in diffusetype hepatocellular carcinoma (DHCC).Methods42 DHCC patients were treated with conventional ultrasound, ultrasonic imaging and enhanced CT performance．ResultsThe accuracy identify DHCC of conventional ultrasonography, CEUS and contrast enhanced CT were was 38% (16/42), 81% (34/42) and 83% (35/42). The accurate diagnosis rates in the CEUS and contrastenhance CT were significantly higher than that in the conventional ultrasonography (P＜0．05)．There was no difference between CEUS and contrast-enhance CT． Conclusions Compared with conventional ultrasonography，CEUS can increase the diagnostic accuracy in the DHCC.That is similar to contrastenhance CT．