【Abstract】 Objective To explore the effect of different high concentration oxygen intermittent inhalation combined with chest pumping in the treatment of idopathic stable and slight pneumothorax.Methods 129 idopathic stable and slight pneumothorax patients were divided into Group A, Group B and Group C. Group A (40 cases) was treated with oxygen flow rate 5～6L / min, 2 hours each time, three times a day. Group B (44 cases) was treated with oxygen flow rate 7～8L / min, 1 hour each time, twice a day. Group C (45 cases) was treated with oxygen flow rate of 8 ～10L / min, 30 minutes each time, twice a day. The patients with pulmonary compression more than 30% got immediate chest pumping treatment when hospitalized. Patients with lung compression confirmed less than＜30% by chest Xrays. The curative effect was observed.Results There was significant difference (P＜0.001) in lung compression before and after the oxygen therapy in the three groups of highconcentration oxygen inhalation combined with chest pumping treatment (P＜0.01). The three high oxygen concentration groups can speed up the absorption of pneumothorax and had significant effect in closed pneumothorax. There was significant difference among group A, group B and C in aspects of the lung compression degree, lung resuscitation time and hospitalization time (P＜0.01), while no significant difference between group B and group C (P＞0.05). There were significant statistic differences of pulse and blood oxygen saturation (P＜0.01) among the three groups. Selfrating anxiety scales displayed significant difference among the three groups (P＜0.01).Conclusion If the patients cant tolerate pure oxygen inhalation, the masked intermittent inhalation of 7～10L / min oxygen flow combined with chest pumping treatment can achieve a satisfactory effect and shorten hospital stay. In the treatment of idiopathic, stable and slight pneumothorax, intermittent masked inhalation 7～ 8L / min of oxygen flow can also achieve the same clinical effect. If possible, Idiopathic small pneumothorax patients with stable conditions can be treated with ECG monitoring, and get the disease education and mental nursing after hospital admission, reduce the anxiety of patients and help them accelerate the healing of pneumothorax.