【Abstract】 Chronic kidney disease (CKD) is a worldwide public health problem, with high cost of therapy, and poses a great challenge to the utilization of public health resources. The standardized and reasonable assessment, regular health education, implementation of a healthy lifestyle and integrated management of CKDrelated risk factors are important on delay the progress of CKD, prevent cardiovascular events and improve the quality of life in CKD patients. In this paper, the protection of key endpoints of CKD is reviewed.