Objective To explore the clinical value of dynamic contrast-MRI(DCE-MRI),diffusion weighted imaging(DWI)in diagnosis of prostate cancer.Methods 35 patients with prostate cancer and 28 patients with hyperplasia of prostate were underwent with a routine scan,DWI and DCE-MRI.Image analysis for prostate cancer and prostate hyperplasia taken respectively for lesions oven diffusion weighted signal change,measure the apparent diffusion coefficient(ADC),Dynamic enhancement peak arrival time,and the change over time in delay scan.Results In DWI sequence can,the patients with prostate cancer were significantly high signal,while ADC decrease.The cases with hyperplasia of prostate DWI sequence signal were not significantly increased and ADC values were not significantly reduced.In DCE scanning,prostate cancer group was rapidly strengthened,while in delay scan,it slowed down or continued to strengthen,but the degree of reinforcement generally did not rise.In hyperplasia of prostate group,the nodules were gradually strengthened,and in delay scan the degree of strengthen increased.Conclusion DCE-MRI and DWI could present the specific findings in the diagnosis of prostate cancer.The combining application of the two examination methods will further increase the accurate diagnosis of prostate cancer.